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Bone Substitutes in Oral Implantology

CE- Bone Substitutes in Oral Implantology
Launch Course

Course Objectives (1 CE Credit)

Randolph R. Resnik, DMD, MDS

Adequate bone volume is one of the most important prerequisites for predictable implant placement and osseointegration. Therefore, in order to establish an ideal site for implant placement, it is paramount to restore the loss of bone volume that can result from trauma, tooth loss or tooth extraction. Bone regeneration procedures are widely accepted as a viable option for the treatment of edentulous spaces to be restored with an implant-supported prosthesis. Dr. Resnik examines the concept of bone regeneration, fundamentals of bone biology, and bone graft material options available to the implant clinician. Topics include:

  • Ideal characteristics of bone graft material
  • Mechanisms of bone healing
  • Macroscopic and microscopic features of bone
  • Bone cell types involved in the regeneration process
  • Biological properties of osteoregeneration
  • Graft material options, considerations and indications


Bone substitutes have been an important treatment option in implant dentistry. In deciding which bone graft material to use, the clinician must have a clear understanding of how bone heals and be able to distinguish the ideal bone material for the specific case and situation. Ideally, a bone regeneration material should be cost-effective, non-immunogenic, easily handled, and resorbed in unison with new bone formation. Applying a strong understanding of bone biology to the selection of bone substitutes helps to maximize the success of implant treatment in areas where deficient bone volume is present.


  1. Liu J, Kerns DG. Mechanisms of guided bone regeneration: a review. Open Dent J. 2014 May 16;8:56-65.
  2. Van der Weijden F, Dell’Acqua F, Slot DE. Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. J Clin Periodontol. 2009 Dec;36(12):1048-58.
  3. Hof M, Tepper G, Semo B, Arnhart C, Watzek G, Pommer B. Patients’ perspectives on dental implant and bone graft surgery: questionnaire-based interview survey. Clin Oral Implants Res. 2014 Jan;25(1):42-5.
  4. Sanz M, Vignoletti F. Key aspects on the use of bone substitutes for bone regeneration of edentulous ridges. Dent Mater. 2015 Jun;31(6):640-7.
  5. Boyce T, Edwards J, Scarborough N. Allograft bone: the influence of processing on safety and performance. Orthop Clin North Am. 1999 Oct;30(4):571-81.
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